Home > Research Teams > Complex Trait Genetics > Key Publications

2010

Bosker FJ, Hartman CA, Nolte IM, Prins BP, Posthuma D, van Veen T, Willemsen G, de Rijk R, de Geus EJ, Hoogendijk WJ, Sullivan PF, Penninx BW, Boomsma DI, Snieder H, Nolen WA. Poor replication of candidate genes for major depressive disorder using genome-wide association data. Mol Psychiat, in press (IF12.5)

Brans R, Kahn R, Schnack H, van Baal C, Posthuma D, van Haren N, Lepage C, Lerch J, Collins L, Evans A, Boomsma D, Hulshoff Pol H. Brain plasticity and intellectual ability are influenced by shared genes. J Neurosc, in press (IF7.5)

Colzato LS, Waszack F, Nieuwenhuis S, Posthuma D, Hommel B The flexible mind is associated with Catechol-O-methyltransferase Val158Met polymorphism: Evidence from switching between tasks, Neuropsychologia. 2010 Apr 29 (IF 4.1)

Dupuis et al. Novel genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet, 2010 Feb;42(2):105-16 (IF30.3)

Hoekstra RA, Vinkhuyzen AAE, Wheelwright S, Bartels M, Boomsma DI, Baron-Cohen S, Posthuma D, van der Sluis S. Brief report: the construction and validation of an abridged version of the Autism-spectrum quotient (AQ-short), J Autism Dev Disord. 2010, PMID: 20697795 (IF3.1)

Liu Y, Blackwood DH, Caesar S, de Geus EJ, Farmer A, Ferreira MA, Ferrier IN, Fraser C, Gordon-Smith K, Green EK, Grozeva D, Gurling HM, Hamshere ML, Heutink P, Holmans PA, Hoogendijk WJ, Hottenga JJ, Jones L, Jones IR, Kirov G, Lin D, McGuffin P, Moskvina V, Nolen WA, Perlis RH, Posthuma D, Scolnick EM, Smit AB, Smit JH, Smoller JW, St Clair D, van Dyck R, Verhage M, Willemsen G, Young AH, Zandbelt T, Boomsma DI, Craddock N, O’Donovan MC, Owen MJ, Penninx BW, Purcell S, Sklar P, Sullivan PF. Meta-Analysis of Genome-Wide Association Data of Bipolar Disorder and Major Depressive Disorder. Molecular Psychiatry, 2010 Mar 30. (IF 12.5)

Loos, M., van der Sluis, S., Bochdanovits, Z., van Zutphen, I.J., Pattij, T., Stiedl, O., Neuro-BSIK Mouse Phenomics consortium, Smit, A.B. & Spijker, S. (2009). Activity and impulsive action are controlled by different genetic and environmental factors. Genes Brain & Behavior. 8(8), 817-828.

Polderman, T. J. C., Boomsma, D. I., Bartels, M., Verhulst, F. C., Huizink, A. C. (2010). Attention Problems and Academic Achievement during childhood: a systematic review of prospective studies. Acta Psychiatrica Scandinavica, 122, 271-284. (IF3.7)

Ruano D, Abecasis GR, Glaser B, Lips ES, de Jong APH, Evans DM, Davey Smith G, Timpson NJ, Smit AB, Heutink P, Verhage M, Posthuma D. Functional gene-group analysis reveals a role of synaptic heterotrimeric G-proteins in cognitive ability. Am J Hum Genet, 2010;86(2):113-25. (IF10.2)

Segrè AV; DIAGRAM Consortium; MAGIC investigators, Groop L, Mootha VK, Daly MJ, Altshuler D. Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits. PLoS Genet. 2010;6(8). (IF 9.5)

Smit DJA, Boersma M, van Beijsterveldt CEM, Posthuma D, Boomsma DI, Stam CJ, de Geus EJC. Endophenotypes in a dynamically connected brain. Behav Genet, 10.1007/s10519-009-9330-8. Online Jan 28, 2010, (IF3.3)

Thomsen, S.F., van der Sluis, S., Kyvik, K.O., Skytthe, A., & Backer, V. (2010). Estimates of asthma heritability in a large twin sample. Clinical & Experimental Allergy, 40, 1054–1061

Tobacco and Genetics Consortium. Genome-wide meta-analyses identify multiple loci associated with smoking behavior. Nat Genet. 2010 May;42(5):441-7 (IF30.3)

Van der Sluis, S., Kan, K.J., & Dolan, C.V. (2010). Consequences of a network view for genetic association studies. Commentary on “Comorbidity, a network perspective” by Cramer, A.O.J., Waldorp, L.J., van der Maas, H.L.J., & Borsboom, D. Behavioral and Brain Sciences, 33, 173-174.

van der Sluis S, Vinkhuyzen AAE, Boomsma DI, Posthuma D. Sex differences in adults’ motivation to achieve. Intelligence, in press

Vinkhuyzen AAE, van der Sluis S, Boomsma DI, de Geus EJC, Posthuma D. Individual Differences in the Sternberg Paradigm. Behav Genet, in press, (IF3.3)

Vinkhuyzen AAE, van der Sluis S, Boomsma DI, de Geus EJC, Posthuma D Genetic Influences on Environmental Factors. Genes, Brain, Behav, In press (IF3.9)

Vinkhuyzen AAE, van der Sluis S, Posthuma D Life Events Moderate Variation in General IQ in Adults, Mol Psychiat, available online Feb 16, 2010 (IF12.5)

Visscher PM & Posthuma D. Statistical Power to Detect Genetic Loci Affecting Environmental Sensitivity. Behavior Genetics, 2010 Apr 29. (IF3.3)

2009

Bochdanovitz et al. Joint re-analysis of twenty-nine correlated SNPs supports the role of PCLO/Piccolo as a causal risk factor for major depressive disorder, Mol Psychiat, 2009;14(7):650-2 (IF12.5)

Bochdanovits Z, Gosso MF, van den Berg L, Rizzu P, Polderman TJC, Pardo LM, de Geus EJC, Boomsma DI, Heutink P, Posthuma D. A functional non-synonymous polymorphism under positive evolutionary selection in the beta-2 adrenergic receptor explains phenotypic differences in intelligence among humans. Behav Genet, 2009;39(1):15-23. (IF3.3)

De Moor MHM, Liu Y, Boomsma DI, Li J, Drees BM, Hamilton JJ, Hottenga JJ, Levy S, Liu X, Pei Y, Papasian CJ, Posthuma D, Recker RR, Sullivan PF, Wang L, Willemsen G, Yan H, Jin T, De Geus EJ, Deng H. Genome-wide association study of leisure-time exercise behavior in Dutch and American adults. Medicine & Science in Sports & Exercise, 2009 Sep 2. [Epub ahead of print] (IF2.9)

Haworth CM, Wright MJ, Martin NW, Martin NG, Boomsma DI, Bartels M, Posthuma D, Davis OS, Brant AM, Corley RP, Hewitt JK, Iacono WG, McGue M, Thompson LA, Hart SA, Petrill SA, Lubinski D, Plomin R.A twin study of the genetics of high cognitive ability selected from 11,000 twin pairs in six studies from four countries. Behav Genet. (doi: 10.1007/s10519-009-9262-3). (IF3.3)

Haworth C.M.A., Wright M.J., Luciano M., Martin N.G., de Geus E.J.C., van Beijsterveldt C.E.M., Bartels M., Posthuma D., Boomsma D.I., Davis O.S.P., Kovas Y., Corley R.P., DeFries J.C., Hewitt J.K., Olson R.K., Rhea S.A, Wadsworth S.J., Iacono W.G., McGue M., Thompson L.A., Hart S.A., Petrill S.A., Lubinski D, & Plomin R. The heritability of general cognitive ability increases linearly from childhood to young adulthood. Mol Psychiat, 2009 Jun 2. [Epub ahead of print] (IF12.5)

Jonker MA, Bhulai A, Boomsma DI, Ligthart RS, Posthuma D & van der Vaart A,. (2008). Gamma frailty model for linkage analysis with application to interval censored migraine data. Biostatistics, 2009;10(1):187-200 (IF3.0)

Polderman TJ, de Geus EJ, Hoekstra RA, Bartels M, van Leeuwen M, Verhulst FC, Posthuma D, Boomsma DI. Attention problems, inhibitory control, and intelligence index overlapping genetic factors: A study in 9-, 12-, and 18-year-old twins. Neuropsychology. 2009;23(3):381-91 (IF3.1)

Pardo L, Bochdanovits Z, de Geus E, Hottenga JJ, Sullivan P, Posthuma D, Penninx BWJH, Boomsma D, Heutink P. Global similarity with local differences in linkage disequilibrium between the Dutch and HapMap CEU populations. Eur J Hum Genet, 2009;17(6):802-10. (IF3.9)

Posthuma D, de Koning DJ, Dolan CV, Goddard ME, Visscher PM. A note on permutation tests for genetic association analysis of quantitative traits when variances are heterogeneous, Genet Epidemiol,2009;33(8):710-6. (IF5.2)

Smit DJ, Posthuma D, Boomsma DI, De Geus EJ. Phenotypic and genetic correlations between evoked EEG/ERP measures during the response anticipation period of a delayed response task. Psychophysiology. 2009;46(2):344-56. (IF3.3)

Sullivan et al., (including Posthuma D) Genomewide Association for Major Depressive Disorder: A possible role for the presynaptic protein Piccolo. Mol Psychiat. 2009;14(4):359-75. (IF12.5)

The Psychiatric GWAS Consortium. A framework for interpreting genomewide association studies of psychiatric disorders. Mol Psychiat, 2009;14(1):10-7 (IF12.5)

The Psychiatric GWAS Consortium. Genomewide association studies: History, rationale and prospects for psychiatric disorders. Am J Psychiat, 2009;166(5):540-56. (IF10.5)

Thomsen S, van der Sluis S, Stensballe L, Posthuma D, Skytthe A, Kyvik K, Duffy D, Backer V, Bisgaard H. Exploring the association between severe respiratory syncytial virus infection and asthma: a registry-based twin study. Am J Respir Crit Care Med, 2009; 179(12):1091-7 (IF9.1)

Vinkhuyzen AAE, van der Sluis S, Posthuma D, Boomsma DI. The heritability of aptitude and exceptional talent across different domains. Behav Genet, 2009;39(4):380-92 (IF3.3)

2008

de Geus E, Goldberg T, Boomsma DI, Posthuma D. Imaging the genetics of brain structure and function. Biol Psychol. 2008, 79(1):1-8.(IF4.0)

Gosso MF, de Geus EJC, Polderman TJC, Boomsma DI, Heutink P, Posthuma D. (2008). Catechol O-methyl transferase and dopamine D2 receptor gene polymorphisms: evidence of positive heterosis and gene-gene interaction on working memory functioning. Eur J Hum Genet, 16(9):1075-1082.(IF3.9)

Gosso MF, de Geus EJC, Polderman TJC, Boomsma DI, Heutink P, Posthuma D. Common variants underlying cognitive ability: further evidence for association between the SNAP-25 gene and cognition using a family-based study in two independent Dutch cohorts. Genes, Brain, Behav, 2008;7(3):355-64.(IF3.9)

Luciano M, Lind PA, Deary IJ, Payton T, Posthuma D, Butcher LM, Heutink P, Whalley LJ, Visscher PM, Harris SE, Polderman TJC, Davis OSP, Wright MJ, Starr JM, de Geus EJC, Bates TC, Montgomery GW, Boomsma DI, Martin NG, Plomin R. Testing replication of a 5-SNP set for general cognitive ability in six population samples. Eur J Hum Genet, 16(8):1025. (IF3.9)

Middeldorp CM, Hottenga JJ, Slagboom PE, Sullivan PF, de Geus EJ, Posthuma D, Willemsen G, Boomsma DI. Linkage on chromosome 14 in a genome-wide linkage study of a broad anxiety phenotype. Mol Psychiat. 2008;13(1):84-9 (IF12.5)

van der Sluis S, Dolan CV, Neale MC, Posthuma D. (2008). A General Test for Gene-Environment Interaction in Sib Pair-based Association Analysis of Quantitative Traits. Behav Genet. 38(4):372-89 (IF3.3)

Smit DJ, Stam CJ, Posthuma D, Boomsma DI, de Geus EJ. (2008). Heritability of “small-world” networks in the brain: A graph theoretical analysis of resting-state EEG functional connectivity. Hum Brain Mapp. 29(12):1368-78. (IF6.2)

van der Sluis S, Derom C, Thiery E, Bartels M, Polderman TJC, Verhulst FC, Jacobs N, van Gestel S, de Geus EJC, Dolan CV, Boomsma DI, Posthuma D. (2006). Sex differences on the WISC-R in Belgium and The Netherlands. Intelligence, 36(1) 2008:48-67 (IF 3.8)

Van der Sluis S, Dolan CV, Neale MC, Posthuma D. (2008). Power calculations using exact data simulation: a useful tool for genetic study designs. Behav Genet. 38(2):202-11 (IF3.3)

van der Sluis, S, Willemsen G, de Geus EJC, Boomsma DI, Posthuma D. (2008). Gene-environment interaction in adults’ IQ scores: measures of past and present environment. Behav Genet, 8(4):348-60 (IF3.3)

Webbink D, Posthuma D, Boomsma DI, de Geus EJC, Visscher PM (2008).The cognitive cost of being a twin in the Netherlands. Intelligence, 36(6):539-547 (IF 3.8)

2007

de Moor MHM, Posthuma D, Hottenga JJ, Willemsen G, Boomsma DI, EJC De Geus EJC. Genome-wide linkage scan for exercise participation in Dutch sibling pairs: Eur J Hum Genet. 2007, 15(12):1252-9. (IF3.9)

Goedhart, A. D., Van der Sluis, S., Houtveen, J. H., Willemsen, G., & de Geus, E. J. C. (2007). Comparison of time and frequency domain measures of RSA in ambulatory recordings. Psychophysiology, 44, 203-215.

Gosso MF, de Geus EJC, Polderman TJC, Boomsma DI, Posthuma D, Heutink P. (2007). Exploring the functional role of the CHRM2 gene in human cognition: results from a dense genotyping and brain expression study. BMC Med Genet. 2007, 8:66. (IF2.8)

Hottenga JJ, Whitfield JB, Posthuma D, Willemsen G, de Geus EJC, Martin NG, Boomsma DI. (2007). Genome-wide scan for blood pressure in Australian and Dutch subjects suggests linkage at 5p, 14q and 17p. Hypertension, 2007;49(4):832-8 (IF6.0)

Kuijper EAM, Lambalk CB, Boomsma DI, van der Sluis S, Blankenstein MA, de Geus EJC, Posthuma D. (2007). Heritability of reproductive hormones in adult male twins. Hum Reprod, 22(8):2153-9 (IF3.8)

Mekel-Bobrov N*, Posthuma D*, Gilbert SL, Lind P, Gosso MF, Luciano M, Harris SE, Bates TC, Polderman TJC, Whalley LJ, Fox H, Starr JM, Evans PD, Montgomery GW, Fernandes C, Heutink P, Martin NG, Boomsma DI, Deary IJ, Wright MJ, de Geus EJC, Lahn BT. The ongoing adaptive evolution of ASPM and Microcephalin is not explained by increased intelligence. Hum Mol Genet, 16(6):600-8. (IF7.2)

Polderman TJC, Derks EM, Hudziak JJ, Verhulst FC, Posthuma D, and Boomsma DI (2007). Across the continuum of Attention Skills: A twin study of the SWAN ADHD rating scale. J Child Psychol Psychiat, 48:11, 1080-1087 (IF4.9)

Polderman TJC, Posthuma D, De Sonneville LMJ, Stins J, Verhulst FC, Boomsma DI. (2007). Genetic analyses of the stability of executive functioning during childhood. Biol Psychol, 76(1-2):11-20(IF4.0)

Silventoinen K, Posthuma D, Lahelma E, Rose RJ, Kaprio J (2007). Genetic and environmental factors affecting self-rated health from age 16 to 25: a longitudinal study of Finnish twins. Behav Genet, 37, 326-333. (IF3.3)

Silventoinen K, Bartels M, Posthuma D, Estourgie-van Burk GF, Willemsen GF, van Beijsterveldt CEM, Boomsma DI. Genetic regulation of growth in height and weight from three to 12 years of age: a longitudinal study of Dutch twin children. Twin Res Hum Genet, 10(2):354-63 (IF2.1)

Smit DJA, Posthuma D, Boomsma DI, De Geus EJC (2007). The Relation between Frontal EEG Asymmetry and the Risk for Anxiety and Depression. Biol Psychol, 74, 26-33. (IF4.0)

Smit DJA, Posthuma D, Boomsma DI, De Geus EJC. Genetic contribution to the P3 in Young and Middle-aged Adult Subjects. Twin Res Hum Genet 10(2):335-47 (IF2.1)

Smit DJA, Posthuma D, Boomsma DI, De Geus EJ. Heritability of anterior and posterior visual N1. Int J Psychophysiol. 2007,66(3):196-204 (IF2.7)

Thomsen SF, Ulrik CS, Kyvik KO, Sørensen TIA, Posthuma D, Skadhauge LR, Steffensen I, Backer V. (2007). Association between obesity and asthma in a large sample of twins. Allergy, 62(10):1199-204(IF6.2)

Van der Sluis, S., de Jong, P. F., & van der Leij, A. (2007). Executive functioning in children, and its relations with reasoning, reading, and arithmetic. Intelligence, 35, 427-449.

2006

Boomsma DI, Cacioppo JT, Slagboom PE, Posthuma D. (2006). Genetic linkage and association analysis for loneliness in Dutch twin and sibling pairs points to a region on chromosome 12q23-24. Behav Genet, 36(1):137-46. (IF3.3)

Boomsma DI, de Geus EJC, Vink JM, Stubbe JH, Distel MA, Hottenga JJ, Posthuma D, van Beijsterveldt TCEM, Hudziak JJ, Bartels M, Willemsen G (2006). Netherlands Twin Register: From Twins to Twin Families. Twin Res, 9(6):849-57. (IF2.1)

Dolan, C.V., Colom, R., Abad, F.J., Wicherts, J.M., Hessen, D.J., & Van der Sluis, S. (2006). Multi-group covariance and mean structure modeling of the relationship between the WAIS-III common factors and sex and educational attainment in Spain. Intelligence, 34(2), 193-210.

Gosso MF, de Geus EJC, van Belzen MJ, Polderman TJC, Heutink P, Boomsma DI, Posthuma D. (2006). The SNAP-25 gene is associated with cognitive ability: Evidence from a family based study in two independent Dutch cohorts. Mol Psychiat, 11(9):878-886 (IF12.5)

Gosso MF, van Belzen M, de Geus EJC, Polderman JC, Heutink P, Boomsma DI, Posthuma D (2006). Family based association testing provides further evidence for a role of the CHRM2 gene in cognition. Genes, Brain, Behav, 5(8), 577-584. (IF3.9)

Hillman CH, Motl RW, Pontifex MB, Posthuma D, Stubbe JH, Boomsma DI, De Geus EJC. Physical activity and cognitive function in a cross-section of younger and older community-dwelling individuals. Hlth Psychol., 25(6):678-87. (IF3.7)

Hulshoff Pol HE, Schnack HG, Posthuma D, Mandl RCW, Baaré WF, van Oel C, van Haren NE, Collins DL, Evans AC, Amunts K, Bürgel U, Zilles K, Geus EJC, Boomsma DI, Kahn RS. A genetic neural network involved in human intelligence. J Neurosc, 26(40):10235-42. (IF7.5)

Nieuwenhuis S, Stins JF, Posthuma D, Polderman TJC, Boomsma DI, & de Geus EJC. (2006). Accounting for sequential trial effects in the flanker task: Conflict adaptation or associative priming? Mem Cog, 34(6):1260-72. (IF1.6)

Polderman TJC, Gosso MF, Posthuma D, van Beijsterveldt CEM, Heutink P, Verhulst FC, Boomsma DI. A Longitudinal Twin Study on IQ, Executive Functioning, and Attention Problems During Childhood and Early Adolescence. Acta Neurologica Belgica, 106, 191-207 (IF2.3)

Polderman JC, Posthuma D, De Sonneville LMJ, Verhulst FC, Boomsma DI. (2006) Genetic analyses of teacher ratings of problem behavior in 5-year-old twins. Twin Research, 9(1):122-30. (IF2.1)

Polderman TJC, Stins JF, Posthuma D, Gosso MF, Verhulst FC, Boomsma DI.(2006). The phenotypic and genotypic relation between working memory speed and capacity. Intelligence, 34, 549-560. (IF3.8)

Posthuma D, Cherny SS, Boomsma DI. (2006). Introduction to the Special Issue: Human Linkage Studies for Behavioral Traits. Behav Genet, 36(1):1-3. (IF3.3)

Posthuma D, & de Geus, EJC. (2006). Progress in the molecular genetic study of intelligence. Cur Dir Psych, 15(4), 151-155. (IF3.4)

Posthuma D, Visscher PM, Willemsen G, Zhu G, Martin NG, Slagboom PE, de Geus EJC, Boomsma DI (2006) Replicated linkage for eye color on 15q using comparative ratings of sibling pairs. Behav Genet 36(1):12-7. (IF3.3)

Silventoinen K, Posthuma D, van Beijsterveldt CEM, Bartels M, Boomsma DI Genetic and environmental contributions to the association between height and intelligence from young childhood to middle age: evidence from Dutch twin data. Genes, Brain, Behav, 5(8):585-95. (IF3.9)

van der Sluis S, Dolan CV, Neale MC, Boomsma DI, Posthuma D. (2006). Detecting Genotype-Environment interaction in MZ twin data: the Jinks & Fulker test and a new test based on Marginal Maximum Likelihood estimation. Twin Res, 9(3):377-92. (IF2.1)

van der Sluis S, Posthuma D, Dolan CV, de Geus EJC, Colom R, Boomsma DI (2006). Sex differences on the Dutch WAIS-III. Intelligence, 34,273-289. (IF3.8)

Vink JM, Posthuma D, Slagboom PE, Neale MC, Boomsma DI (2006). Genome-wide linkage scan to identify loci for age at first cigarette in Dutch sibling pairs. Behav Genet, 36(1):100-11. (IF3.3)

2005

de Craen AJM, Posthuma D, Remarque EJ, van den Biggelaar AHJ, Westendorp RGJ, Boomsma DI (2005). Heritability estimates of innate immunity: an extended twin study. Genes Immun, 6, 167-170. (IF4.0)

de Geus EJC*, Posthuma D*, Kupper HM, van den Berg M, Willemsen G, Beem AL, Slagboom PE, Boomsma DI (2005). A whole genome scan for 24-hour respiration rate: a major locus at 10q26 influences respiration during sleep. Am J Hum Genet, 76:100–111 . (IF10.2)

Dolan, C.V., Van der Sluis, S., & Grasman, R. (2005). A note on normal theory power calculation in structural equation modeling with data missing completely at random. Structural Equation Modeling, 12(2), 245-262.

Heijmans BT, M. Beekman M, Putter H, Lakenberg N, van der Wijk HJ, Whitfield JB, Posthuma D, Pedersen N, Martin NG, Boomsma DI, Slagboom PE, (2005) Meta-analysis of four new genome scans for lipid parameters and analysis of positional candidates in positive linkage regions. Eur J Hum Genet, 13(10):1143-53. (IF3.9)

Hottenga JJ, Boomsma DI, Kupper N, Posthuma D, Snieder H, Willemsen G, de Geus EJC. (2005). Heritability and stability of resting blood pressure. Twin Research, 8(5), 499-508. (IF2.1)

Kupper HM, Willemsen AHM, Posthuma D, De Boer D, Boomsma DI, De Geus EJC (2005). A genetic analysis of ambulatory cardiorespiratory coupling. Psychophysiology, 42(2):202-12. (IF3.3)

Kupper N, Willemsen G, Riese H, Posthuma D, Boomsma DI, de Geus EJC. (2005). Heritability of ambulatory blood pressure in an extended twin design. Hypertension, 45:1-6. (IF6.0)

Luciano M, Posthuma D, Wright MJ, de Geus EJC, Smith GA, Geffen GM, Boomsma DI, Martin NG (2005). Perceptual speed does not cause intelligence, and intelligence does not cause perceptual speed. Biol Psychol, 70, 1-8. (IF4.0)

Posthuma D, Boomsma DI (2005). Mx Scripts Library: Structural equation modeling scripts for twin and family data. Behav Genet, 35(4) 499-505. (IF3.3)

Posthuma D, de Geus EJC, Mulder EJCM, Smit DJA, Boomsma DI & Stam CJ. (2005). Genetic components of functional connectivity in the brain: the heritability of synchronization likelihood. Hum Brain Mapping, 26, 191-198. (IF6.2)

Posthuma D, Luciano M, de Geus EJC, Wright MJ, Slagboom PE, Montgomery GW, Boomsma DI , Martin NG A genome-wide scan for intelligence identifies quantitative trait loci on 2q and 6p. Am J Hum Genet 77(2),318-26. (IF10.2)

Posthuma D, Meulenbelt I, de Craen AJM, de Geus EJC, Slagboom PE, Boomsma DI, Westendorp RGJ. (2005). Amyloid-β induced inflammatory response is mediated by genetic factors. Twin Res, 8(2) 132-137. (IF2.1)

Smit DJA, Posthuma D, Boomsma DI, De Geus EJC (2005) Heritability of Background EEG across the Power Spectrum. Psychophysiology, 42, 691-697. (IF3.3)

Stubbe JH, Posthuma D, Boomsma DI & de Geus EJC. (2005). Heritability of life satisfaction in adults: a twin-family study. Psychol Med, 35(11), 1581-8. (IF4.2)

Van der Sluis, S., Dolan, C.V., Stoel, R.D. (2005). A note on testing perfect correlations in SEM. Structural Equation Modeling, 12 (4), 551-577. (IF: 2.14)

Van der Sluis, S., van der Leij, A., & de Jong, P. F. (2005). Working memory in Dutch children with reading and arithmetic related learning deficits. Journal of Learning Disabilities, 38 (3), 207 – 221.

Willemsen G, Posthuma D, Boomsma DI. (2005). Environmental factors determine where the Dutch live: Results from the Netherlands Twin Register. Twin Res, 8(4), 312-317. (IF2.1)

2004

Beekman M, Posthuma D, Heijmans BT, Lakenberg N, Suchiman HED, Snieder H, de Knijff P, Frants RR, van Ommen GJB, Kluft C, Vogler GP, Slagboom PE, Boomsma DI. (2004) Combined association and linkage analysis applied to the APOE locus. Genet Epidemiol 26(4), 328-337. (IF5.2)

Heijmans BT, Beem AL, Willemsen AHM, Posthuma D, Slagboom PE, Boomsma DI (2004). Further evidence for a QTL influencing body mass index on chromosome 7p from a genome-wide scan in Dutch families. Twin Res, 7(2), 192-196. (IF2.1)

Kupper N, Willemsen G, van den Berg M, de Boer D, Posthuma D, Boomsma DI, de Geus EJC (2004). Heritability of ambulatory heart rate variability. Circulation, 110: 2792 – 2796. (IF10.9)

Posthuma D, de Geus EJC, Boomsma DI, and Neale MC. (2004) Combined linkage and association tests in Mx. Behav Genet, 34 (2), 179-195. (IF3.3)

van den Berg SM, Posthuma D, Boomsma DI. (2004). A longitudinal genetic study of vocabulary knowledge in adults. Twin Res, 7(3), 284-291. (IF2.1)

Van der Sluis, S., de Jong, P. F., & van der Leij, A. (2004). Inhibition and shifting in children with learning deficits in arithmetic and reading. Journal of Experimental Child Psychology, 87, 239-266.

Vink, JM, Beem AL, Posthuma D, Neale MC, Willemsen AHM, Kendler KS, Slagboom PE, Boomsma DI. (2004). Linkage analysis of smoking initiation and quantity in Dutch sibling pairs. The Pharmacogenomics Journal, 4, 274-282. (IF5.4)

Willemsen G, Boomsma DI, Beem AL, Vink JM, Slagboom PE, Posthuma D. (2004). QTLS for height: results from a full genome scan in Dutch sibling pairs. Eur J Hum Genet, 12(10):820-828. (IF3.9)

2003

Posthuma D, Baaré WFC, Hulshoff Pol HE, Kahn RS, Boomsma DI, de Geus EJC. (2003). Genetic correlations between brain volumes and the WAISIII dimensions of verbal comprehension, working memory, perceptual organization and processing speed. Twin Res, 6(2), 131-139. (IF2.1)

Posthuma D, Beem AL, Geus EJC de, Baal GCM Van, Bornemann Hjelmborg J von , Iachine I, Boomsma DI (2003) Theory and Practice in Quantitative Genetics. Twin Res, 6(5), 361-376. (IF2.1)

Rietveld MJH, Posthuma D, Dolan CV, Boomsma DI. (2003). Sibling interaction effects and ADHD: A note on statistical power. Behav Genet, 33(3), 247-255. (IF3.3)

2002

Bastiaansen MCM, Posthuma D, Groot PFC, de Geus EJC. (2002). Event-related alpha and theta responses in a visuo-spatial working memory task. Clin Neurophysiol, 113, 1882-1893. (IF3.0)

Boomsma DI, Vink JM, van Beijsterveldt CEM, de Geus EJC, Beem AL, Mulder EJCM, Riese H, Willemsen AHM, Bartels M, van den Berg M, Derks EM, de Graaff SC, Kupper HM, Polderman JC, Posthuma D, Rietveld MJH, Stubbe JH, Knol LI, Stroet Th, van Baal GCM (2002) Netherlands Twin Register: a focus on longitudinal research, Twin Res, 5, 401-406. (IF2.1)

Hulshoff Pol HE, Posthuma D, Baaré WFC, de Geus EJC, Schnack HG, van Haren NE, van Oel CJ, Kahn RS, Boomsma DI. (2002). Twin singleton differences in brain structure using structural equation modeling. Brain, 125, 384-390. (IF9.6)

Moxley G, Posthuma D, Carlson P, Estrada E, Han J, Benson LL, and Neale MC. (2002). Sexual Dimorphism in Innate Immunity. Arthritis & Rheumatism, 46(1), 250-258. (IF7.8)

Posthuma D, de Geus EJC, Baaré WFC, Hulshoff Pol HE, Kahn RS, Boomsma DI (2002). The association between brain volume and intelligence is of genetic origin. Nat Neurosc, 5(2), 83-84. (IF14.2)

Posthuma D, Mulder EJCM, Boomsma DI, de Geus EJC. (2002). Genetic analysis of IQ, processing speed and stimulus-response incongruency effects. Biol Psychol, 61, 157-182. (IF4.0)

Vogelaar SA, Posthuma D, Boomsma D, Kluft C. (2002). Blood sample stability at room temperature for counting red and white blood cells and platelets. Vascular Pharmacology, 39, 123-125. (IF2.3)

2001

Baaré WFC, Hulshoff Pol HE, Boomsma DI, Posthuma D, de Geus EJC, Schnack HG, van Haren NE, van Oel CJ, Kahn RS (2001) Quantitative genetic modeling of human brain morphology variation. Cereb Cortex, 11, 816-824. (IF5.9)

de Geus EJC, Posthuma D, IJzerman RG, Boomsma DI (2001) Comparing blood pressure of twins and their singleton siblings: being a twin does not affect adult blood pressure. Twin Res, 4, 385-391. (IF2.1)

Posthuma D, de Geus EJC, Boomsma DI. (2001). Perceptual speed and IQ are associated through common genetic factors. Behav Genet, 31(6), 593-602. (IF3.3)

Posthuma D, Neale MC, Boomsma DI, de Geus EJC. (2001). Are smarter brains running faster? Heritability of alpha peak frequency, IQ and their interrelation. Behav Genet,31(6), 567-579. (IF3.3)

Wright MJ, de Geus EJC, Ando J, Luciano M, Posthuma D, Ono Y, Hansell NK, van Baal GCM, Hiraishi K, Hasegawa T, Smith GA, Geffen GM, Geffen LB, Kanba S, Miyake A, Martin NG, Boomsma DI. (2001). Genetics of cognition: outline of a collaborative twin study. Twin Res, 4(1):48-56. (IF2.1)

2000

Posthuma D, Boomsma DI. (2000). A note on the statistical power in extended twin designs. Behav Genet 30, 147-158. (IF3.3)

Posthuma D, de Geus EJC, Bleichrodt N, Boomsma DI. (2000). Twin-singleton differences in intelligence? Twin Res, 3:83-87. (IF2.1)

Posthuma D, de Geus EJC, Neale MC, Hulshoff Pol HE, Baaré WFC, Kahn RS, Boomsma DI. (2000) Multivariate genetic analysis of brain structure in an extended twin design. Behav Genet, 30:311-319. (IF3.3)

National (refereed) journals

Posthuma D. (2003) Erfelijkheid en intelligentie. (2003), Neuropraxis, 7(3), 83-88 (Dutch).

Posthuma D, Lange, A. (1999). Positieve zelfverbalisatie bij opgenomen patienten; een pilot-onderzoek. Directieve Therapie, 3. 134-145. (in Dutch)

Bookchapters

2010 Vinkhuyzen AAE, van der Sluis S, Posthuma D. Behavior Genetics. In: Integrative Clinical Psychology, Psychiatry, and Behavioral Medicine: Perspectives, Practices, and Research, Ed. Roland A. Carlstedt

2009 Nelis A & Posthuma D. Zoek de verschillen … Over intelligentie, erfelijkheid en tweelingenonderzoek. in: de Maakbare Mens, onder redactie van Koops, Nelis, Sieburgh, Luty. Center for Society and Genomics, Nijmegen (in Dutch)

2009 Posthuma D. Multivariate Genetic Analysis. In: Handbook of Behavior Genetics. Yong Kyu Kim, Ed. Springer, 2009

2009 Posthuma D, de Geus EJC, Deary IJ. The genetics of intelligence. In: The Genetics of Cognitive Neuroscience. Terry Goldberg & Daniel Weinberger, Eds. MITT Press.

2008 Posthuma D (2008) Intelligentieonderzoek bij tweelingen. In: Tweelingonderzoek – Een fascinerende wetenschap. Onder redactie van Boomsma (in Dutch)

2008 Posthuma D, & de Geus E. (2008). The Genetics of Information Processing Speed in Humans. In: J DeLuca and J Kalmar (Eds.). Processing Speed in Clinical Populations, Taylor and Francis, pp. 79-100

2007 van der Sluis S, and Posthuma D. Single Locus Association Models. In: Dissection of complex trait variation through linkage and association. Editors: M Ferreira, B Neale, SE Medland, D Posthuma. Taylor & Francis, UK, pp. 323-354

2007 Posthuma D and Maes HH. Variance Components Linkage Analysis for Quantitative Traits. In: Dissection of complex trait variation through linkage and association. Editors: M Ferreira, B Neale, SE Medland, D Posthuma. Taylor & Francis, UK, pp 181-206.

2005 Posthuma D. (2005). Additive Genetic Variance. Encyclopedia in Statistics for Behavioral Sciences Vol. 1. Eds: B Everitt, D Howell, John Wiley and Sons, Ltd, Chichester, pp. 18-22.

2005 Boomsma D, Willemsen G, De Geus E, Kupper N, Posthuma D, IJzerman R, Heijmans B, Slagboom E, Beem L, Dolan C (2005). Twins and the fetal origins hypothesis: An application to growth data. In: Hormones and the Brain, C. Kordon, R.C. Gaillard, Y. Christen (Eds.), 29-46, Springer.

2002 Meijer, J., Oostdam, R., & Van der Sluis, S. A feasibility study into incremental predictive validity of dynamic assessment of verbal-reasoning ability. In D. G. M. van der Aalsvoort, W. C. M. Resing & A. J. J. M. Ruijssenaars (Eds.), Learning potential assessment and cognitive training: Actual research and perspectives in theory building and methodology (Vol. 7, pp. 273-293). Oxford: Elsevier Science.

2002 Posthuma D, Bartels M, Boomsma DI. (2002). De gedragsgenetische benadering van veroudering. In: Schroots, J.J.F. (Red.) Handboek psychologie van de volwassen ontwikkeling en veroudering. Assen: Van Gorcum. (Dutch) p.137-155.

2002 Posthuma D, de Geus EJC, Boomsma DI. (2002). Genetic contributions to anatomical, behavioural, and neurophysiological indices and cognition. In: R. Plomin, J.C. deFries, I.C. Craig, & P. McGuffin (Eds.). Behavioral genetics in the postgenomic era. Washington, DC. APA Books. 2002. p.141-162.

Books

2007 Statistical Genetics: Gene Mapping Through Linkage and Association. (2007) Eds. Neale, Ferreira, Medland, Posthuma. Taylor and Francis, London, UK. (ISBN 9780415410403)

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