Our mission is to study the brain and its disease mechanisms through an integrative approach running from molecule-to-bedside. We apply a systems biology approach of the brain where clinicians and clinical researchers are working side-by-side with neuroscientists, geneticists, psychologists, biophysicists and statisticians. Through this collaboration we aim at delivering proof-of-concept for radically new approaches in the early diagnosis of brain disease, the elucidation of its underlying mechanisms, and thus providing new perspectives on therapy.

We focus on the biological mechanisms underlying common mental health and neurological brain diseases, applying the latest technology and thereby providing new perspectives on therapy. Finding the ‘cause’ of brain diseases, design its ‘cure’ and implement this to the level of ‘patient care’ are all in the center of our research ambition. All research in the ‘brain disease mechanisms’ programs is aimed and integrated with our major in-house patient clinics, including the Center for children with White Matter Disorders and the GGZBA-clinic affiliated patient research-programs for Anxiety and Depression disorders (NESDA) of the GGZBA-clinic.