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"We are interested in the neural basis of cognitive and emotional-motivational processes and their disturbances in major neuropsychiatric disorders" |
Prof.
Dr. H.J. (Henk) Groenewegen |
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"We are dealing with the interconnections and functional relationships of prefrontal cortex, basal ganglia and limbic structures like the amygdala and the ventral striatum. In other words, we map the neuronal circuits involved in cognitive processes and we are interested in the neurotransmitters involved, receptors and their plasticity. Our goal is to establish correlations between structural and functional or dysfunctional aspects of the brain circuits involved.”
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Publications: Voorn P, Vanderschuren LJMJ, Groenewegen HJ, Robbins TW, Pennartz CMA.. Putting a spin on the dorsal-ventral divide of the striatum. Trends in Neuroscience. 2004; 27:468-474. Van den Heuvel OA, Veltman DJ, Groenewegen HJ, Cath DC, Van Balkom AJLM, van Hartskamp J, Barkhof F, Van Dyck R. Frontal-striatal dysfunction during planning in obsessive-compulsive disorders. Archives Gen Psych. 2005; 62:301-309. Van Dongen YC, Deniau JM, Pennartz CM, Galis-de Graaf Y, Voorn P, Thierry AM, Groenewegen HJ. Anatomical evidence for direct connections between the shell and core subregions of the rat nucleus accumbens. Neuroscience. 2005;Oct 12; [Epub ahead of print].
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